Found 12 matching trials
Study of BGB-290 or Placebo in Participants With Advanced or Inoperable Gastric Cancer PHASE2 This study enrolled participants with previously-treated advanced or inoper...
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Miami Cancer Institute
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Study of the Efficacy, Safety and Pharmacokinetics of Pamiparib (BGB-290) in Participants With Advanced Solid Tumors PHASE1 This study is designed to evaluate the safety, tolerability, PKharmacokinet...
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Cancer Hospital Chinese Academy of Medical Sciences
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Study to Investigate the Effect of Rifampin and Itraconazole on the Action of Pamiparib in Participants With Cancer PHASE1 The study was an open-label, parallel-group, fixed-sequence study in male a...
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Arensia Exploratory Medicine Llc
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BGB-290 and Temozolomide in Treating Patients With Recurrent Gliomas With IDH1/2 Mutations PHASE1 This phase I/II trial studies the side effects and how well BGB-290 and tem...
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UAB Comprehensive Cancer Center
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Pamiparib and Low Dose Temozolomide In Patients With Platinum Sensitive Biliary Tract Cancer PHASE2 The main objective of this trial is to evaluate the activity of pamiparib p...
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Multiple Locations
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Study to Assess Safety, Tolerability and Clinical Activity of BGB-290 in Combination With Temozolomide (TMZ) in Participants With Locally Advanced or Metastatic Solid Tumors PHASE1 The primary objective of this study was to determine the safety and tolerab...
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Pamiparib in Fusion Positive, Reversion Negative High Grade Serous Ovarian Cancer or Carcinosarcoma With BRCA1/2 Gene Mutations If Progression on Substrate Poly ADP Ribose Polymerase Inhibitbor (PARPI) or Chemotherapy PHASE2 This study is a phase II, multi-centre, open label study in patients with a...
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Multiple Locations
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Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-Pamiparib in Participants With Advanced Cancer PHASE1 This is an open-label study, in participants with advanced and/or metastati...
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The Clatterbridge Cancer Centre NHS Foundation Trust
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Neoadjuvant Intense Endocrine Therapy for High Risk and Locally Advanced Prostate Cancer PHASE2 This is a prospective, multicenter, multi-arm, non-randomized, open-label c...
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Department of Urology, Drum Tower Hospital, Medical School of Nanjing University, Institute of Urology, Nanjing University
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Treatment of Metastatic Castration-Resistant Prostate Cancer With Homologous Recombination Deficiency PHASE2 This study is designed to evaluate the efficacy of pamiparib in participant...
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University Cancer and Blood Center
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